Mission

The Alter Foundation is dedicated to reversing molecular aging and extending human healthspan through scientific research.

Current Work

We built a high-throughput, parallelized version of a magnetic enrichment device to culture and purify aged Saccharomyces cerevisiae using a biotin-streptavidin system. This platform enables scalable selection of old yeast cells, starting from a fob1Δ background known for its extended replicative lifespan.

We apply a genetic algorithm-inspired selection process to iteratively enrich for yeast lineages that live longer. Once long-lived colonies are isolated, we perform omics analyses to uncover the molecular mechanisms driving their longevity, with the goal of translating these findings to higher-order organisms. In parallel, we conduct genome-wide iterative deletion screens to identify combinatorial gene knockouts that extend lifespan, further revealing genetic determinants of aging.

Contact

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i = 0;

while (!deck.isInOrder()) {
    print 'Iteration ' + i;
    deck.shuffle();
    i++;
}

print 'It took ' + i + ' iterations to sort the deck.';

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Name Description Price
Item One Ante turpis integer aliquet porttitor. 29.99
Item Two Vis ac commodo adipiscing arcu aliquet. 19.99
Item Three Morbi faucibus arcu accumsan lorem. 29.99
Item Four Vitae integer tempus condimentum. 19.99
Item Five Ante turpis integer aliquet porttitor. 29.99
100.00

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Name Description Price
Item One Ante turpis integer aliquet porttitor. 29.99
Item Two Vis ac commodo adipiscing arcu aliquet. 19.99
Item Three Morbi faucibus arcu accumsan lorem. 29.99
Item Four Vitae integer tempus condimentum. 19.99
Item Five Ante turpis integer aliquet porttitor. 29.99
100.00

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